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Research & Development

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Aarti Industries Limited (AIL) has evolved from being a vendor to becoming a partner of choice. Our four state-of-the-art R&D centres located at Dombivali and Navi Mumbai in Maharashtra, and Vapi in Gujarat, continuously work towards developing new products and finding a way to make by-products marketable. Equipped with modern machinery and dedicated laboratories, these research centres promise to further enhance the product portfolio and improve the manufacturing process.

Our R&D centres focus on new product development and creating solutions to convert our by-products into gainful products. A latest addition to our research capabilities is a large state-of-the-art research and technology centre at Navi Mumbai.

Our strategic focus is to become a reference in speciality chemicals and pharmaceuticals globally. In the long-run, we aim to further embrace open innovation and create a purposeful and sustainable organisation.

Backed by our expertise, technical know-how, experience and resources, we are ready to embrace growth opportunities and play a pivotal role in cementing our presence in the global chemical industry.

Expertise In Specific Chemistry

AIL has developed expertise in following chemistries:

Plant Scale:
  • Ammonolysis
  • Condensation
  • Chlorination
  • Denitrochlorination
  • Diazotization
  • Ethylation
  • Halex (Fluorination)
  • Hydrogenation
  • Nitration
  • Sulphonation
Lab Scale:
  • Alkylation
  • Acetylation
  • Amino Acid Esterification
  • Aldol Condensation
  • Asymmetric Hydrogenation
  • Benzidine Rearrangement
  • Bromination/Sandmeyer
  • Butyl Lithium Reaction
  • Balz-Schiemann Reaction
  • Boron Chemistry
  • Carboxylation
  • Cynation
  • Cyclocondensation
  • Chichibabin Reaction
  • Chiral Chemistry
    (Implementation of enzymatic technology)
  • Dehydrogenation
  • Denitrochlorination
  • Diborane Reduction
  • Darzens Glycidic Ester Condensation
  • Dieckmann Cyclization
  • Esterification
  • Epoxidation
  • Fluorination: KF, AHF, DHF
    and Balz Schiemann
  • Friedel Crafts Reaction
  • Flow reactor technology at
    commercial scale
  • Grignard's Reaction
  • Hydrogenation/Dehalogenation
    /Reductive amination
  • Hetero Diels Alder Reaction
  • Kolbe Schmitt Reaction
  • Knoevenagel Reaction
  • Methoxylation
  • Meerwein-Pondorf-Verley Reduction
  • Michael Addition
  • Negishi Reaction
  • Oxidation
  • Oppenauer Oxidation
  • Organometallic Coupling:
    Grignard/Kumada/Suzuki
  • Phosphorylation
  • Phosgenation
  • Ring Alkylation
    and N-alkylation
  • Sulfonation
  • Silylation
  • Sandmeyer Reaction
  • Suzuki Coupling
  • Swern Oxidation
  • Skraup Reaction
  • Steroid Chemistry
  • Triphosgene Reactions
  • Ullamann Reaction
  • Vapour phase reaction:
    Ammoxidation/Isomerisation
  • Vilsmeier-Haack Reaction
  • Witting Reaction
  • Willegrodt Reaction

Analytical Capability

AIL has a state-of-the-art analytical laboratory spread over 6,500 sq. ft. with an experienced and qualified team of scientists.

Chemical composition analysis applies combination of techniques that can cover a wide range of applications to obtain quantitative and qualitative information by determining chemical quality, identity, composition and potential impurities, with molecular structure elucidation and chemical structure confirmation.

  • Development by scientific approach
  • Validation characteristics as per applicable regulatory guidelines
  • Customer method verification for suitability of performance Structural Elucidation
  • Master standard preparation by qualification of reference and impurity standards
  • Characterisation of impurity and standards by using of several spectral techniques
  • Purification and isolation of impurity by prep-HPLC and flash chromatography to support and supply of impurities specified in the quality specification
  • Analytical technology transfers to quality units with predefined method acceptance criteria by applying regulatory expectations on interlaboratory analytical studies
  • Long term and accelerated stability studies to understand the impact of temperature and humidity on products over the period of time to define the validity
  • Packaging compatibility studies of products
  • Waste characterisation studies of process wastes to comply the regulatory agencies requirements
  • Scientific data and records are maintained over centralised CDS software under access-control and with watertight data security and protection
  • The laboratories are paperless, with concepts such as Electronic Laboratory Notebooks (ELN), Scientific Data Management Systems (SDMS), Laboratory Information Management Systems (LIMS) and SAP.
  • Chromatography: HPLC, UPLC, GC, Ion Chromatography, Prep-HPLC, Flash Chromatography
  • Spectroscopy: GC-MS, LC-MS, ICP-MS, FT-IR, UV-Visible, NMR 300Mz (collaborative)
  • Wet Analysis: Vol/Coulometry KF, Autotitrators, pH Measurements, BOD/COD, Tintometer, Microbalance
  • Stability Studies: Stability Chambers (2-8°c, 25°c 60%RH, 40°c 75%RH), Hygroscopicity, Photo stability, Holding Time To Study
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Synthesis Capability

An ultra-modern
synthesis laboratory spread
over  18000 sq. feet  of space
Having

100

+ PhD and postgraduate
scientists

Fully Digitised Paperless Laboratory

Our facility in Navi Mumbai is a fully paperless laboratory. Using Electronic Laboratory Notebook system, experiments are recorded online and analysis requests and results are uploaded electronically along with the final reviews.

The paperless laboratory offers a database enriched with the details of experimental work spread over a span of three decades. It has provided our scientists with ready access to intelligent and experimental insights. The concept reduces duplication of work and allows our team to learn from the past and improvise in the future.

Other advantages include seamless inter-departmental communication, confidentiality and security of data, ease of use and researching experiments.

Reaction Workstations

Reaction workstations are established to conduct various unit reactions

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Strategic Chemistry and Technology Development

Based on the business requirement, a dedicated team of scientists develops certain strategic chemistries contributing towards multiple growth projects.

Following strategic chemistries are being developed:

Process Safety Studies

Health, safety and environmental impact are key to product development. We have a dedicated process safety team and a process safety laboratory.

During the R&D process, our teams follow stringent process safety data management practices which generate process safety data that is utilised for in-house Process safety Risk Assessment (HAZOP).

There are essentially four major hazards in chemical processing:

Health and environment hazards are identified through the in-house SDS generated through SDS authoring software which is GHS compliant.

The chemical reaction hazards that may be generated during the chemical processing/storage. The three major chemical reaction hazards are:

  • Thermal instability of reactants, reactant mixtures and products (including any intermediates, residues, wastes, potential contaminants and by-products)
  • Exothermic reactions which raise the temperature to produce decomposition reactions or violent boiling
  • Gas evolution

A dedicated team equipped with advanced laboratory equipment conducts different process safety studies.

  • Thermal stability studies
    • Differential scanning calorimeter-DSC (Mettler)
    • Thermal Screening Unit - TSU (HEL)
    • Vent size packaging-VSP-2 (Fauske and associate)
  • Exothermic Reaction Studies
    • Reaction Calorimeter - RC1 (Mettler) (Atmospheric and Medium pressure vessel)
  • Gas Evolution Studies
    • Gas Evolution - as a co-product in desired reaction
      Gas Evolution measurement apparatus along with reaction calorimeter
    • Gas Evolution in the undesired reaction
      Thermal Screening Unit - TSU (HEL)
      Vent size packaging-VSP-2 (Fauske and associate)
  • Vent sizing
    • Vent size packaging-VSP-2 (Fauske and associate)

We also plan to include the following equipment shortly to turn our facility into a complete Chemical Reaction Hazard assessment facility.

1. Accelerating rate calorimeter-ARC (THT)
2. Reaction Calorimeter - RC (optimisation (up to 100bar) Hastelloy vessel)

We carry out thermal stability tests and other fire and explosion tests especially for powder safety testing. For quick results of powder safety testing, we have also extensive tie ups with third-party service providers. The data from these tests is assessed in-house in our laboratories.

We also plan to include the following equipment shortly for fire and explosion hazards

1. Minimum ignition energy-MIE
2. RFlash point

We undertake Hazop studies during the R&D process development to ensure our processes are inherently safe.

We have developed a Safety Data Sheet (SDS) which is a central database of all the GHS compliant products and chemicals being used at AIL. This online database is readily accessible to all employees.

In addition, an open communication channel for our products and requests for MSDS button is live on the website.

Waste Pre-treatment Studies

We are also setting up a waste pre-treatment study laboratory. The aim is to reduce the effluent load and treat it in the most economic and environment-friendly manner. A dedicated team will be assigned to treat the following parameters to achieve the CETP norms in aqueous and organic waste: