Aarti Industries is a knowledge-driven Company. Aarti presently has three R&D centers; two, located in Dombivali and Vapi, focus on R&D initiatives for Pharmaceutical APIs, and the other, located in Vapi, on Chemicals. Another 50,000 sq ft R&D and Innovation Complex, which will house 150 scientists and engineers, is in the works. The complex will double Aarti’s R&D capabilities and focus on development of newer and niche value-added products and process chemistries, and improving product quality and process yields of existing products, forward integration for downstream products, among others. The complex is planned to comprise of an R&D centre, a scale-up facility, an Innovation Center, and dedicated labs for Process Safety, Effluent Treatment and Flow Chemistry, among others.
Atmospheric reactions are carried out in jacketed glass reactors. The reactors are equipped to measure and control process parameters precisely. This has enabled Aarti to apply Design of Experiment during process intensification. It also uses PAT tools such as react-IR and online particle size to monitor the progress of reaction and take critical decisions. This reduces the incidence of manual errors and produces reliable results.
A dedicated high pressure section has been developed with ballast proof walls. The reactors are controlled by DCS to avoid any exposure to research personnel. Further, software-controlled gas feeding, temperature control, cooling, and liquid feeding has been employed to obtain reliable data. This allows a thorough analysis of abnormal thermochemical activity in the process.
The laboratory is equipped with lab scale modules for various types of workup equipments used in the plant, including Buchner Funnels, Nutsche Filter, and Centrifuge Filter. Also, rotavapors are used for solvent recovery.
Aarti frequently employs distillation employed as a purification step. So, Aarti has procured a sophisticated distillation apparatus that can achieve separation of compounds with boiling point difference of around 1 °C. This setup provides flexibility to change theoretical plates and reflux ratios. Lab data helps in scaling up and designing pilot and plant-scale distillation setup.
Parallel reactors are being used for high throughput screening of reaction parameters and process optimization using statistical design of experiments.
Aarti’s capabilities include carrying out photochemical reactions in the batch reactors.
Aarti is a manufacturing solution provider for chemical syntheses of various kinds. Aarti uses flow chemistry to increase the safety of the process . There are several advantages this process has over traditional batch chemistry
Aarti’s analytical team employs procedures like gravimetric, volumetric, colorimetric and potentiometric for chemical testing in the wet lab. Using these, the team obtains quantitative and qualitative information relating to elements in a sample.
Chemical composition analysis utilizes a combination of techniques that can cover a wide range of applications. These determine chemical quality, identity, composition and impurities, with molecular structure elucidation and chemical structure confirmation.
Chemical trace analysis is often complex. Aarti’s trace chemical testing capabilities include trace metals analysis and organic compound detection up to trace and ultra-trace ranges, even for complex sample matrices.
ICP Spectrometers perform trace element analysis, detecting the full spectrum of elements. These machines have detection limits in the parts per million range for many metals, and even parts per trillion for a few.
Chemical residues testing includes analysis, detection and identification of residues and this expertise is regularly deployed to solve industry problems.
The analytical laboratory also performs testing on metals to determine susceptibility to corrosion. The list of services provided for corrosion testing include accelerated intergranular corrosion, passivation, humidity, salt spray and salt fog methods performed according to ASTM and industry standards.
At the R&D stage, Aarti has defined philosophies and procedures to be followed when designing a safe chemical reaction process. These concentrate on the hazards that may be generated during the chemical reaction.
The three major chemical reaction hazards are:
Aarti has developed a central database of MSDS involving all the chemicals being used at our sites. This online database is readily accessible to all employees.
Aarti is planning to setup a dedicated ETP division with an aim to reduce the effluent load and treat it in an economic and environment friendly way.